Norethisterone

Norethisterone
Synonyms: ENT;NET;Norfor; sc4640;Anovule;Gestest
CAS NO.: 68-22-4
Molecular Formula: C20H26O2
Molecular Weight: 298.42
Appearance: Off-White to Pale Yellow Solid
Package: according to clients requirement
Standard: BP2002, EP4
Usage: Progesteron. Norethindrone and acetate in combination with estrogen as contraceptive (oral). It is reasonably anticipated to be a human carcinogen
Description:
Norethisterone (or norethindrone) (or 19-nor-17α-ethynyltestosterone) is a molecule used in some combined oral contraceptive pills, progestogen only pills and is also available as a stand-alone drug. It is a progestogen and can be used to treat premenstrual syndrome, painful periods, abnormal heavy bleeding, irregular periods, menopausal syndrome (in combination with oestrogen), or to postpone a period. It is also commonly used to help prevent uterine hemorrhage in complicated non-surgical or pre-surgical gynecologic cases. Norethindrone was the first orally highly active progestin to be synthesized. It was synthesized for the first time by chemists Luis Miramontes, Carl Djerassi, and George Rosenkranz at Syntex in Mexico City in 1951. It was the progestin used in one of the first three oral contraceptives. Its related ester, norethisterone acetate, is used for the same indications
Applications :
Norethisterone contains a hormone which is similar to the hormoneprogestogen that is naturally produced by the body. It is used to treat a number of menstrual cycle disorders. Norethisterone is also used to help treat breast cancer.
This leaflet discusses norethisterone when it is used to treat heavy periods. Although other treatment options for heavy periods are more common, norethisterone is sometimes considered if other treatments have not worked or are unsuitable. Norethisterone treatment aims to reduce the amount of blood loss. When taking norethisterone in this way, it does not act as a contraceptive.
Treating certain menstrual problems or uterine problems (eg, abnormal bleeding, endometriosis). It may also be used for other conditions as determined by your doctor.Norethindrone is a progestin hormone. It works by altering the lining of the uterus.
COA:

Product name     Norethindrone    
Appearance    White crystalline powder    
Water    ≤5%     pass    
Assay    98 .0~ 102.0%     99.2%    
Loss on drying    ≤0.5%      0.15%    
Related substances     total impurities ≤1.0%     Pass    
any individual impurity     ≤0.5%     Pass    
Residual solvents     ethanol ≤0.5%     Pass    

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